For the best experience on the Abcam website please upgrade to a modern browser such as Google Chrome
If you continue without changing your cookie settings, we'll assume you’re happy with this.
JNK are multifunctional kinases involved in many physiological and pathological processes. Of the three existing isoforms, JNK1 and JNK2 are ubiquitously expressed while JNK3 is mainly expressed in neuronal and heart tissue. Activation of JNK plays a vital role in apoptosis, insulin resistance, inflammatory response and neural polarity.